use
1. Organic synthesis of raw materials, can be used to produce ethylene glycol. Glycolic acid is mainly used as a cleaning agent. It can produce fiber dyeing agent, cleaning agent, welding agent ingredients, varnish ingredients, copper corrosion agent, adhesive, oil demulsifier and metal chelating agent, etc. Sodium salt and potassium salt of glycolic acid are used as additives for electroplating solution. Other uses are electrolytic grinding, metal pickling, leather dyeing and tanning agents. It can also be used as a chemical analysis reagent. [2]
2. Used as a cleaning agent, it can fully react with the rust scale, calcium salt and magnesium salt in the equipment to achieve the purpose of descaling, and it is easy to remove the calcium carbonate scale and iron scale, with good treatment effect. The corrosion to the material is very low, and the precipitation of organic acid iron will not occur during cleaning. Chemical cleaning with glycolic acid is less dangerous and easy to operate. [2]
3. Used in organic synthesis and printing and dyeing industry. [2]
4. Used for sterilization of soap. [2]
5. Glycolic acid is used as a complexing agent for electroless nickel plating to improve the coating quality, and can also be used as an additive for other electroplating or electroless plating. [2]
Medical application
Intratumoral injection of percutaneous hepatocellular carcinoma is an important means to treat hepatocellular carcinoma. Acetic acid is an effective drug for intratumoral injection of hepatocellular carcinoma. However, percutaneous acetic acid injection in the treatment of liver cancer is still limited in the penetration of tumors, difficult to make sustained release preparations, and causes pain in patients during injection. In order to overcome this shortcoming, glycolic acid was introduced into the treatment of liver cancer by intraperitoneal injection as a highly effective chemical inactivator. It was confirmed that glycolic acid has a strong inhibitory effect on tumor cells in vitro, liver necrosis in rats and transplanted liver cancer in nude mice. At the same time, glycolic acid was prepared into liposomes, and chitosan modified liposomes were prepared. The encapsulation rate and release in vitro were investigated, and the therapeutic effect of glycolic acid liposomes on transplanted tumors in nude mice was studied. [8]
In the study of the efficacy of glycolic acid solution, different concentrations of glycolic acid solution were prepared and tested in cells, rats and nude mice, and the efficacy was compared with the same concentration of acetic acid solution. Through cell experiment, it was found that glycolic acid had strong inhibitory effect on liver tumor cells. The average diameter of the maximum cross section of liver necrosis induced by glycolic acid was larger than that caused by the same concentration of acetic acid (P 0.05). The average diameter of nude mice after intraperitoneal injection of glycolic acid was smaller than that of the same concentration of glycolic acid (P 0.05), and the stronger inhibitory effect of glycolic acid was further confirmed by light microscopy and electron microscopy.
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